Hoʻolauna o ke ʻano II Collagen
He aha ke ʻano o ka collagen type II?
ʻO ke ʻano II collagen he protein fibrillar i hana ʻia me 3 mau kaulahao lōʻihi o nā waikawa amino e hana i kahi pūnaewele paʻa paʻa o nā fibrils a me nā fibers. ʻO ia ka mea nui o ka cartilage i loko o ke kino. Aia i loko o ke kaumaha maloʻo a me nā collagens.
ʻO ke ʻano II collagen ka mea e hāʻawi ai i ka cartilage i kona ikaika tensile a me ka elasticity, a laila hiki iā ia ke kākoʻo i nā hono. Kōkua ia i ke kaʻina hana paʻa me ke kōkua o fibronectin a me nā collagens ʻē aʻe.
He aha ka ʻokoʻa ma waena o ke ʻano II a me ke ʻano I collagen?
Ma ka ʻili he ʻano like lākou, ʻo kēlā me kēia mea he triple helix ie i hana ʻia me ʻekolu kaulahao loloa o nā waikawa amino. Eia nō naʻe, ma kahi pae molekala he ʻokoʻa koʻikoʻi.
ʻAno I kolagen: ʻElua o nā kaulahao ʻekolu i like.
ʻAno II collagen: Ua like nā kaulahao ʻekolu.
Loaʻa ka Collagen Type I i loko o nā iwi a me ka ʻili. ʻOiai ʻo ke ʻano II collagen aia wale nō i ka cartilage.
He aha nā pōmaikaʻi o ka collagen type II i ke kino?
E like me kā mākou i ʻike ai, ʻo ke ʻano II collagen kahi ʻāpana nui o ka ʻiʻo cartilage. No laila, no ka hoʻomaopopo pono ʻana i kāna hana, pono e nānā i ka hana o ka cartilage i loko o ke kino.
ʻO Cartilage kahi ʻiʻo pili paʻa akā paʻa. Aia nā ʻano like ʻole o ka cartilage i ke kino, kēlā me kēia me kahi hana kikoʻī. ʻO ka cartilage i loaʻa i loko o nā hono he nui nā hana, e like me
- hoʻohui iwi
- ka ʻae ʻana i ka ʻiʻo e amo i ke koʻikoʻi mechanical
- hoʻopaʻa haʻalulu
- ka ʻae ʻana i nā iwi i hoʻopili ʻia e neʻe me ka ʻole o ka hakakā
Hoʻokumu ʻia ka cartilage me nā chondrocytes he mau cell kūikawā e hana i ka mea i ʻike ʻia he 'extracellular matrix' me ka proteoglycan, elastin fibers a me ke ʻano II collagen fibers.
ʻO ke ʻano II collagen fibers ka mea nui collagenous i loaʻa i ka cartilage. He kuleana koʻikoʻi ko lākou. Hoʻokumu lākou i kahi pūnaewele o nā fibrils e kōkua i ka hoʻopaʻa ʻana i ka proteoglycan a me ka elastin fibers i loko o kahi ʻiʻo paʻakikī, akā hiki ke maʻalahi.